The Country-led Assessment for Prioritisation on Immunisation (CAPACITI) project aims to strengthen the ability of LMICs to evaluate immunisation options according to their priorities and programme context, both for national immunisation programme decisions and to inform vaccine supply, research and development. The CAPACITI decision-support tool outlines the steps of a structured recommendation process that is evidence based, context specific and well documented. The tool is appropriate for decision questions that require comparison of two or more options, may involve input from multiple stakeholders, use evidence from across disciplines and/or indicate significant data uncertainty. The tool allows a committee to combine evidence and different stakeholder views to come to a legitimate and credible recommendation.