This WHO checklist is for any organization or person supporting the routine use of evidence in the process of policy-making. This checklist was developed by the WHO Secretariat of Evidence-Informed Policy Network (EVIPNet) to assist its Member countries in their journey of institutionalizing evidence-informed policy-making (EIPM). Government agencies (i.e., the staff of the Ministry of Health), knowledge intermediaries, and researchers focused on strengthening EIPM will find in this checklist some key steps and tools to help their work. While the health sector is a key target group for EVIPNet, it is suggested that this tool can be applied by stakeholders from different social sectors.